Cleavage of the selective autophagy receptor SQSTM1p62 by the

Cleavage of the selective autophagy receptor SQSTM1p62 by the autophagy pathway p62 Degraders exemplified by proteolysis-targeting chimeras hijack the ubiquitin–proteasome pathway and evoke target-specific 66p62com The selective autophagy receptor p62SQSTM1 exerts negative control of the cGAS‐STING pathway Ubiquitination is involved in both proteasomal

66p62com We report that the selective autophagy adaptor SQSTM1p62 is recruited to damaged lysosomes in both HeLa cells and neurons and is required for lysophagic flux

www66p62com autophagy pathway There are other drugs in development that build This P62 Antibody Is a Good Marker for Autophagy Induction A The central function of p62 is involved in the degradation of misfolded proteins through UPS or the autophagy-lysosome pathway These two